Okay, just to add to the confusion.. I have had issues with these blue controllers before. They seem to be very sensitive to being in the right 'place' on initial start up. If they are not in the speed controls perceived neutral, they wont work. I encountered this a few years ago with a specific brand of 2 channel radio..and I cannot remember which one!
My guess, the mixer is confusing the speed controls, confused speed controls are refusing to work, simple diagnosis I think. Problem is, not sure how easy to fix. I think you will need different speed controls. Don't buy Vipers, they do not get on with mixers. The TIO controls are fine with mixers, Action kit is fine and Quicruns are fine ( you will need the 880 not the 1060 as that doesn't go up to 12v).
Maybe to confirm this try enabling one speed control on one channel, with the trim in different places. First in neutral, then all the way up, then all the way down. I think there is a 50% chance in one of those positions it wont enable. Go on, humour me!!
Alan.