I've used sheet and shaped styrene in many areas to great advantage and success over the years. Its easy to work with, can formed relatively easily and takes paint well after priming.
To glue styrene to styrene I've used, for years (and I know there will be a lot of hollering here) MEK. Works fantastic and welds the pieces together. They never come apart, because they are welded together. Testors and Tamiya make a liquid styrene glue that works very well too. Does the same as MEK, but not as lethal.
To fasten styrene to other materials: liquid styrene glue works well when attaching styrene to wood. The softened styrene absorbs into the wood and a good solid bond is made. Cyano can also be used for fastening styrene to other materials, however, roughen the styrene surface first for better adhesion.
Don't forget people like Evergreen make styrene in a wide variety of shapes that is extremely helpful in model making. The also make sheets with different surface textures for, example, tongue and groove siding.
As an example, I built the wheel house, below, using styrene sheet and strips. In the warf scene, the whare house and tanks were built from styrene
John