If you lack experience, charging one at a time is simplest and safest.
But.... two 6v batteries connected in series gives a 12 volt 4.5AH battery. A SLA charger set for 12 volts will not know the difference, and will charge them accordingly, in the same length of time that it took to charge one 6 volt. The other pair could be treated similarly. If this was connected in parallel with the first two, you would have a 12 volt 9 amp-hour battery.
As AAGE says, this depends on the batteries all being in a similar state of charge or discharge, and being in similar condition regarding their ability to be charged.
If there are dissimilarities between elements in a series chain, then uneven charging may result, meaming that the "better" cells will be overcharged, and probably become as bad as the others.
In a parallel network, on connection, they will do their best to even out the voltage between themselves. This can result in massive circulating currents. Because of the construction of lead acid cells, this can in extreme case cause local heating which causes the plates to warp.