With no RC Jamming would not be an option. All the jamming I have ever hear about is mounted of unsophisticated vehicles. Perhaps to stop interference with your own counter measure platform.
If it is autonomous, it would only need to send updates back to base. Communication with base by burst transmission would also make it less detectable.
Basically, if you can get close enough to see it and try to electronically interfere with it, you could shoot it out of the water. As long as it can see you (or your pinging of it), identify you as unfriendly, and travel faster than you, she should be pretty safe.