For home made ones I think a tipping point was around 2002 when Maplin started selling sound recording chips which let you store a sample of a recording and play it back. Of course, shortly after they were found to be useful, they discontinued them as was Maplin's unfortunate habit. But there also appeared greeting card chips. A fraction of the size and cost of the ISD series of chips, and already mounted on their own board, just needing an amplifier to drive a speaker and something to switch them on.
The 555s were amazingly versatile, and did have a 200mA output pin, but it was just switched on or off, not really an audio source. The on-off nature of the outputs needed a conditioning circuit to turn it into a useful waveform ready for amplifying, which is what I suspect most of the bits on Stans board were doing.